The study of viruses and viral diseases. Play Virology trivia solo to sharpen your knowledge, or challenge a friend head-to-head in Trivia Tango — every question comes with an explanation so you learn as you play. Questions span every level, from easy warm-ups to expert-level stumpers, so there's a real challenge here however much you already know.
A mix of easy, medium and hard — questions run from warm-up to expert, so there's a real challenge at every level. Think you know the answers? Play to find out.
This infectious agent is so small it can only reproduce inside a living host cell, causing diseases from the common cold to COVID-19.
Difficulty: EasyWhen a host cell is commanded by an invader to produce thousands of copies that then rupture and destroy it, this replication mode is termed this.
Difficulty: MediumThe Picornavirus VPg protein primes RNA synthesis by covalent linkage to uridine residues through this amino acid side chain that becomes phosphodiester-bonded.
Difficulty: HardEdward Jenner pioneered this medical procedure in 1796 using cowpox material to protect against smallpox.
Difficulty: EasyHIV integrates its DNA into the host chromosome using this enzyme, which is now targeted by drugs like raltegravir and dolutegravir.
Difficulty: MediumNodaviruses replicate their bipartite RNA genome entirely in the cytoplasm by forming replication compartments derived from this organelle's outer membrane.
Difficulty: HardHIV attacks these immune system components that coordinate the body's defenses, leaving patients vulnerable to opportunistic infections.
Difficulty: EasyThese tiny plant pathogens consist only of naked circular RNA without any protein coat, causing diseases in potatoes and other crops.
Difficulty: Medium