Biology Trivia Questions

  • ❓ 79+ questions
  • 🗂️ Biology
  • 🎚️ Easy to expert
  • ✨ Free to play

The science of life and living organisms. Play Biology trivia solo to sharpen your knowledge, or challenge a friend head-to-head in Trivia Tango — every question comes with an explanation so you learn as you play. Questions span every level, from easy warm-ups to expert-level stumpers, so there's a real challenge here however much you already know.

Download on the App StoreGet it on Google Play

Already playing?

Sample Biology Quiz Questions

A mix of easy, medium and hard — questions run from warm-up to expert, so there's a real challenge at every level. Think you know the answers? Play to find out.

  1. These organelles, once free-living bacteria that were engulfed by early eukaryotes, now produce most of a cell's ATP through oxidative phosphorylation.

    Difficulty: Easy
    • Mitochondria
    • Ribosomes
    • Golgi apparatus
    • Endoplasmic reticulum
  2. This nitrogen base pairs exclusively with adenine in DNA through two hydrogen bonds, following Chargaff's rules of base pairing.

    Difficulty: Medium
    • Guanine
    • Thymine
    • Cytosine
    • Uracil
  3. This AAA+ ATPase extracts ubiquitinated proteins from membranes and complexes, unfolding them for proteasomal degradation through its central pore.

    Difficulty: Hard
    • VCP/p97
    • NSF
    • ClpX
    • Lon protease
  4. In this phase of cell division, chromosomes line up along the middle of the cell, attached to spindle fibers at their centromeres.

    Difficulty: Easy
    • Prophase
    • Metaphase
    • Anaphase
    • Telophase
  5. This phase of cellular respiration occurs in the cytoplasm without oxygen and breaks glucose into two pyruvate molecules while producing a small net gain of ATP.

    Difficulty: Medium
    • Glycolysis
    • Krebs cycle
    • Electron transport chain
    • Oxidative phosphorylation
  6. This pathway activates when double-strand breaks are sensed by the MRN complex, leading to ATM kinase activation and p53-mediated cell cycle arrest or apoptosis.

    Difficulty: Hard
    • ATR checkpoint
    • Spindle assembly checkpoint
    • G1/S checkpoint
    • DNA damage response (DDR)
  7. This molecule carries amino acids to the ribosome during protein synthesis, matching its anticodon to messenger RNA codons.

    Difficulty: Easy
    • Messenger RNA
    • Ribosomal RNA
    • Transfer RNA
    • Small nuclear RNA
  8. The portion of an enzyme where substrate molecules bind and undergo chemical transformation is called this.

    Difficulty: Medium
    • Allosteric site
    • Regulatory site
    • Active site
    • Binding pocket

Think You Know Biology?

Play a free round in your browser, learn something new with every answer, and challenge your friends to beat your score.

Or get the app

Download on the App StoreGet it on Google Play